Creatine Dosage

The road to big, strong muscles is long and requires hard work in a gym. But the researchers may have found a shortcut where muscles grow on their own. In fact, scientists have succeeded, through gene therapy, in increasing lean body mass and strength in macaque monkeys. The experiment was quite simple, the researchers simply injected the follistatin gene (FS344) directly into the monkeys’ right thigh muscles.

Follistatin has been shown to block myostatin, a molecule that down-regulates muscle growth, but strengthens tendons. Eight weeks after injection, the circumference of the monkeys’ right thigh muscles had increased by an average of 15 percent compared to the left thigh. A study conducted on two of the monkeys showed that muscle strength in the right leg increased by 12 and 36 percent, respectively, compared to the untreated leg!

Follistatin is injected by means of a viral vector, that is, an Adeno Associated Virus that is used as a transport for the drug that is injected.

It is a common method called gene therapy and has been used in humans with other drugs.

The monkey study showed no negative side effects.

This therapy is being developed for use in patients with severe muscular dystrophy and other muscle wasting disorders.

Human clinical trials will begin in 2011, and Nationwide Children’s Hospital in Ohio has already secured funding for the study. There are a number of studies and clinical trials underway or planned for the treatment of muscle wasting disorders, among some of the most interesting substances are follistatin as a myostatin antagonist,

Ostarine, which is a SARM (selective androgen receptor modulator) and is currently in human clinical trials by GTx Inc. and also another SARM codenamed BMS-564,929 that is being developed by Bristol-Myers Squibb .

The potential for athletes to abuse these substances has led the World Anti-Doping Agency to ban SARMs since 2008.

Until now, only the substance known as “SARMs S4” (Andarine) has reached the market and is being used by a limited number of professional and amateur bodybuilders.

Its anabolic effects are said to be moderate and it has rad 140 price 
been reported to have some temporary side effects, most prominent of which is decreased night vision.

The future of drugs developed for muscle-wasting diseases is sure to be of interest to athletes and others who want to get an extra edge.

The next 5-10 years will see a plethora of substances emerge and some could be good replacements for anabolic steroids.

These drugs will be available through the black market to professional and amateur athletes alike, with unprecedented anabolic effects and almost no negative side effects.

© 2022: Buy-Kinis | GREEN EYE Theme by: D5 Creation | Powered by: WordPress